Qualcomm Institute, University of California San Diego

Voxel-wise resting-state MEG source magnitude imaging study reveals neurocircuitry abnormality in active-duty service members and veterans with PTSD

  • NeuroImage
  • August 2014

Post-traumatic stress disorder (PTSD) is a leading cause of sustained impairment, distress, and poor quality of life in military personnel, veterans, and civilians. The present study showed thatMEGsource imaging technique revealed new abnormalities in the resting-state electromagnetic signals from the PTSD neurocircuitry. Particularly, posterolateral OFC and precuneous may play important roles in the PTSD neurocircuitry model.

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Figure 3. Top panel: abnormal alpha band (8–12 Hz)MEG activity in PTSD; bottom panel: abnormal low-frequency band (1–7 Hz) MEG activity in PTSD. The t-threshold of 2.9 is associated with FDR corrected p b .05.